Dansyl chloride
- CAS No.
- 605-65-2
- Chemical Name:
- Dansyl chloride
- Synonyms
- DNS;dansyl;DNSCL;5-DIMETHYLAMINO-1-NAPHTHALENESULFONYL CHLORIDE;SKL100;AI301174;AI3 01174;AI3-01174;DNS chloride;ansylchloride
- CBNumber:
- CB5696240
- Molecular Formula:
- C12H12ClNO2S
- Molecular Weight:
- 269.75
- MDL Number:
- MFCD00003985
- MOL File:
- 605-65-2.mol
- MSDS File:
- SDS
| Melting point | 72-74 °C(lit.) |
|---|---|
| Boiling point | 371.3±22.0 °C(Predicted) |
| Density | 1.1702 (rough estimate) |
| refractive index | 1.5630 (estimate) |
| storage temp. | 2-8°C |
| solubility | acetone: 50 mg/mL |
| form | powder and chunks |
| pka | 2.38±0.40(Predicted) |
| color | yellow to orange |
| Water Solubility | Soluble in dimethyl fluoride, acetone, chloroform, pyridine, benzene and dioxane. Insoluble in water. |
| Sensitive | Moisture Sensitive |
| Merck | 14,2814 |
| BRN | 2217205 |
| Stability | Hygroscopic, Moisture Sensitive |
| InChIKey | XPDXVDYUQZHFPV-UHFFFAOYSA-N |
| CAS DataBase Reference | 605-65-2(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | QMU9166TJ4 |
| EPA Substance Registry System | 1-Naphthalenesulfonyl chloride, 5-(dimethylamino)- (605-65-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H290-H314 | |||||||||
| Precautionary statements | P260-P280-P303+P361+P353-P305+P351+P338+P310 | |||||||||
| Hazard Codes | C | |||||||||
| Risk Statements | 34 | |||||||||
| Safety Statements | 26-36/37/39-45-3 | |||||||||
| RIDADR | UN 3261 8/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | QK3688000 | |||||||||
| F | 10-21 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29214980 | |||||||||
| NFPA 704 |
|
Dansyl chloride price More Price(52)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 39220 | Dansyl chloride BioReagent, suitable for fluorescence, ≥99.0% (HPLC) | 605-65-2 | 1g | $119 | 2024-03-01 | Buy |
| Sigma-Aldrich | 39220 | Dansyl chloride BioReagent, suitable for fluorescence, ≥99.0% (HPLC) | 605-65-2 | 5G | $481 | 2024-03-01 | Buy |
| Sigma-Aldrich | 39220 | Dansyl chloride BioReagent, suitable for fluorescence, ≥99.0% (HPLC) | 605-65-2 | 50g | $2450 | 2024-03-01 | Buy |
| Sigma-Aldrich | 03641 | Dansyl chloride for HPLC derivatization, ≥99.0% (HPLC) | 605-65-2 | 100mg | $47.3 | 2024-03-01 | Buy |
| Sigma-Aldrich | 311155 | Dansyl Chloride - CAS 605-65-2 - Calbiochem Reagent used for fluorescent labeling of proteins, N-terminal amino acids, and amines. | 605-65-2 | 1G | $77.6 | 2024-03-01 | Buy |
Dansyl chloride Chemical Properties,Uses,Production
Uses
Dansyl chloride or 5-Dimethylaminonaphthalene-1-sulfonyl chloride (CAS 605-65-2) is a fluorogenic reagent used for protein, N-terminal amino acid and peptide detection by reverse phase high performance liquid chromatography (HPLC). It is also used to determine the degree of labeling in chymotrypsin and ovalbumin. It acts as a precursor for the synthesis of other derivatives like dansyl amide.
Dansyl chloride is non-fluorescent until it reacts with amines. The resulting Dansyl amides have environmentally sensitive fluorescence quantum yields and emission maxima along with large Stokes shifts. This environment-sensitive fluorescence property has made Dansyl chloride an important tool for biophysical studies.
Chemical Properties
yellow to orange-yellow crystalline powder
Uses
A fluorogenic reagent for N-terminal derivatization of amino acids and peptides and detection by reverse phase HPLC.
Uses
Dansyl chloride is a fluorogenic reagent used for protein, N-terminal amino acid and peptide detection by reverse phase high performance liquid chromatography (HPLC). It is also used to determine the degree of labeling in chymotrypsin and ovalbumin. It acts as a precursor for the synthesis of other derivatives like dansyl amide.
Uses
In fluorescent labelling, column chromatography, HPLC.
Uses
Reagent for fluorescent labelling of amines, amino acids and proteins.
Definition
ChEBI: Dansyl chloride is an aminonaphthalene and a sulfonic acid derivative.
General Description
Dansyl chloride is a fluorogenic reagent which is typically employed for the derivatization of amino acids.
Biochem/physiol Actions
Dansyl chloride is a sulfonyl chloride compound. It is used to end tag amino groups of peptides and proteins. Dansyl chloride is used for derivatization of free amino acids and amines in neural samples and biological fluids. It is used to study fluorescent conjugates of albumin, protein conformational changes studies and active site characterization.
Safety Profile
Poison by intravenous route, When heated to decomposition it emits very toxic fumes of Cland NOx
Dansyl chloride Preparation Products And Raw materials
Raw materials
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Preparation Products
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21689 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4242 | 58 |
| HaBo Hong Kong Co., Limited. | +86-25-18512596065 | info@habotech.com | CHINA | 933 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9641 | 58 |
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- Dansyl chloride or 5-Dimethylaminonaphthalene-1-sulfonyl chloride (CAS 605-65-2) is a fluorogenic reagent used for protein, N-....
- Dec 23，2019
View Lastest Price from Dansyl chloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2022-02-22 | 5-(Dimethylamino)naphthalene-1-sulfonyl chloride
605-65-2
|
US $0.00 / KG | 1KG | 98.8% | 100 tons | Honest Joy Holdings Limited
|
|
 |
2019-07-06 | Dansyl chloride
605-65-2
|
US $1.00 / KG | 1KG | 98% | 200kg | Career Henan Chemical Co |
-
- 5-(Dimethylamino)naphthalene-1-sulfonyl chloride
605-65-2
- US $0.00 / KG
- 98.8%
- Honest Joy Holdings Limited
-
- Dansyl chloride
605-65-2
- US $1.00 / KG
- 98%
- Career Henan Chemical Co